DOSE-RELATED AMELIORATIVE EFFECTS OF COCONUT WATER (COCOS NUCIFERA L.) ON DOXORUBICIN-INDUCED RENAL INJURY IN MALE WISTAR RATS: BIOCHEMICAL AND HISTOPATHOLOGICAL EVIDENCE
Doxorubicin is an effective anthracycline whose clinical use is limited by organ toxicity, including nephrotoxicity involving oxidative and nitrosative stress, inflammation and tissue remodelling. Coconut water (Cocos nucifera L.) contains antioxidant constituents, but evidence of its effects on doxorubicin-induced ren...