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Author

S. Ochsner

2 papers indexed here

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Open access Sep 2026

Sphingolipid metabolism contributes to sex dimorphism in COPD pathogenesis.

Sex-specific mechanisms in chronic obstructive pulmonary disease (COPD) remain poorly defined. Sphingolipids are bioactive mediators that regulate airway epithelial integrity, inflammation, and bronchial smooth muscle tone, and their dysregulation contributes to airway hyperresponsiveness. We tested whether sphingolipi...

Elisabetta Granato, Xiao-Yun Wang, Yun Zhang et al. · 0 citations
Open access Sep 2026

Mechanosignaling promotes macrophage apoptosis resistance in pulmonary fibrosis via metabolic reprogramming

The mechanisms underlying disease progression in idiopathic pulmonary fibrosis (IPF) and other interstitial lung diseases remain unclear. Increased extracellular matrix stiffness is a hallmark of fibrotic lung diseases, while monocyte-derived macrophages promote fibrosis progression. However, there is limited understan...

Chao He, C. Coarfa, Neftali Garcia et al. · 0 citations

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