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S. Özen

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Open access Aug 2026

Predictive Contribution of p16 Beyond HPV Genotype in the Histopathologic Detection of CIN2+ Lesions: A Real-World Cervical Biopsy Cohort Study

Background: HPV genotype-based stratification estimates cervical disease risk but does not directly measure cellular transformation. We assessed whether p16 and Ki-67 improve prediction of CIN2+ beyond HPV genotype and age in a biopsy-confirmed referral cohort. Methods: This retrospective study included 531 high-risk H...

Eda Güner Özen, S. Özen, Duygu Tanyeri et al. · 0 citations

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