Author

S. Paine

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Open access Aug 2026

117 Transcript-resolved mapping of the m6A RNA modification landscape in glioma using nanopore direct RNA sequencing

Glioblastoma (GBM) remains uniformly fatal despite multimodal therapy. While DNA methylation profiling has transformed brain tumour classification, post-transcriptional RNA modifications remain comparatively underexplored. N6-methyladenosine (m6A) is the most abundant internal RNA modification and regulates splic...

Simon Deacon, Lauryn Walker, Masar Radhi et al. · Neuro-Oncology · 0 citations

#diffusion models Open access Sep 2026

A logistic paradigm to predict molecular glioblastoma on clinical MRI

The logistic strategy achieved high sensitivity and discrimination for identifying mGBM according to CNS WHO 2021 and demonstrated more consistent calibration across observers, which support the further evaluation of the tool, particularly in radiologically atypical mGBM.

Yousif Aldabbagh, F. Bhatti, Nitin Menon et al. · Frontiers in Oncology · 0 citations

Open access Aug 2026

50 Comparative evaluation of long- and short-read methylation-aware sequencing for CNS tumour diagnostics

Comparing methylation-aware sequencing platforms enabling simultaneous epigenomic and genomic profiling in CNS tumours shows robust cross-platform concordance and clinical feasibility for CNS tumour diagnostics.

S. Deacon, Inswasti Cahyani, Nadine Holmes et al. · Neuro-Oncology · 0 citations