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Author

S. Pascolo

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Jul 2026

Abstract B014: Therapeutic Reversal of Tumor Cell Plasticity by EHF mRNA Delivery in Prostate Cancer

This strategy represents a first-in-class opportunity to target tumor plasticity and overcome resistance in advanced prostate cancer with a defined biomarker framework (low EHF expression, plasticity signatures) and compatibility with various delivery platforms.

D. Albino, C. Musumeci, Elisa Storelli et al. · 0 citations
Open access Jul 2026

Chemically synthesized, non-capped and non-polyadenylated peptide-coding RNA efficiently induces antigen-specific CD8+ T cells.

This work shows that short, chemically synthesized RNA oligonucleotides lacking some or all of these features are efficiently translated when they encode epitopes recognized by CD8+ T cells and introduces the possibility that defective or supposedly non-coding RNA may encode human and murine major histocompatibility co...

Julia Frei, D. Eisel, N. Jarzębska et al. · 1 citation

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