S. Porkertova

Immunopeptidomics reveals conserved and abundant Francisella tularensis proteins as immunogenic CD4 T cell antigens in mice.

Human tularemia is caused by infection with the intracellular bacterium Francisella tularensis. The ability of the bacterium to cause a severe pneumonic form of the disease has led to concerns in the field of biodefense and efforts to develop a vaccine. F. tularensis LVS provides partial protection against fully virule...