Author

S. Pradhan-Bhatt

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Open access Sep 2026

Comparability of GFAP and UCH-L1 Measurements Using Handheld and Core Laboratory TBI Plasma Tests and Their Diagnostic Performance for Traumatic Intracranial Lesions.

BACKGROUND Glial fibrillary acidic protein (GFAP) and ubiquitin carboxy-terminal hydrolase L1 (UCH-L1) are cleared by the U.S. Food and Drug Administration (FDA) to aid computed tomography (CT) decision-making in patients with traumatic brain injury (TBI). Two commercial assays, i-STAT TBI Plasma test and Alinity i TBI...

Nathan B. Roberts, C. Gherasim, Ke-Xin Li et al. · The Journal of Applied Labor... · 0 citations

Open access Jan 2026

Integration of GFAP/UCH-L1 Testing into an Emergency Department Concussion Pathway and Calculator to Model TBI Biomarker Impact on Time

Mild traumatic brain injury (mTBI) accounts for 70–90% of all TBI cases and represents a significant burden on emergency departments (EDs) across the United States. Despite its prevalence, mTBI evaluation remains heavily dependent on head computed tomography (CT), contributing to imaging overuse, increased health care...

Jason W. Wilson, Gabrielle Bailey, Makenzie Baker et al. · Neurotrauma Reports · 0 citations