Introduction: Cerebral small vessel disease (CSVD) lesions, including white matter hyperintensities (WMHs), lacunar infarcts, cerebral microbleeds (CMBs), and enlarged perivascular spaces (PVSs) are associated with increased risk of dementia. In this study, we aimed to examine their associations with risk factors, neur...
Z. Chen, S. Raeesi, A. Metz et al.· medRxiv· 0 citations
INTRODUCTION: Cognitively stimulating activity (CSA) is associated with cognitive health, but whether associations with cognitive change differ by life stage and sex remains unclear. METHODS: Data were drawn from Rush cohorts. Participants were 2,614 adults aged 65 years and older (1,965 females; 649 males). CSA during...
S. Goulding, S. Raeesi, J. A. Anderson et al.· medRxiv· 0 citations
INTRODUCTION: Cognitive decline in Parkinsons disease (PD) may reflect interacting neurodegenerative and cerebrovascular processes, but their distinct temporal contributions remain unclear. METHODS: Newly diagnosed, untreated PD participants from the PPMI who were cognitively normal at baseline and had at least three y...
R. Moqadam, H. Azizi, S. Raeesi et al.· medRxiv· 0 citations
Higher education was associated with lower selected Alzheimer's disease neuropathologic measures and weaker associations of tau pathology with cognition among female participants, and longitudinal trajectories were nonlinear.
S. Raeesi, Y. Zeighami, C. Morrison et al.· medRxiv· 0 citations
Examining risk factors collectively provides a clearer understanding of brain health vulnerability and supports multidomain prevention strategies that target clustered modifiable risks.
T. Khudair, S. Raeesi, Yashar Zeighami et al.· GeroScience· 0 citations
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