Author

S. Rhie

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Oct 2026

Abstract C119: Characterizing FOXC1 dysregulation in triple-negative breast cancer to advance precision therapies and reduce cancer health disparities

Breast cancer is the most common cancer in women and the second leading cause of cancer death in the United States. Breast cancer has multiple subtypes defined by the expression of the estrogen receptor (ESR1), progesterone receptor (PGR), and human epidermal growth factor receptor 2 (HER2). Among breast cancer subty...

Chung S. Lee, Huan Cao, Vannah Algador et al. · Cancer Epidemiology, Biomark... · 0 citations

Open access Oct 2026

A single epigenetic repressor controls opposing developmental tempos in human neural and cranial neural crest lineages

The precise timing of lineage specification is essential for embryonic development, yet the epigenetic mechanisms enforcing human developmental tempo remain poorly understood1,2. Heterozygous loss-of-function variants in ZNF462 cause Weiss-Kruszka syndrome (WKS), a pleiotropic disorder characterized by neurodevelopment...

Zeynep Eda Atmaca Duran, Marcella Birtele, S. Mendiratta et al. · bioRxiv · 0 citations

Open access Jul 2026

Decoding 3D chromatin architecture reveals distinct enhancer classes underlying hierarchical gene regulation in prostate cancer

The findings suggest that enhancers function in a coordinated manner, forming multi-connected cancer-specific chromatin interaction hubs, with distinct enhancer classes contributing differently to gene regulation.

Huan Cao, Zexun Wu, Baixi Ji et al. · Genome Biology · 0 citations