Author

S. Rubio-Guerra

2 papers indexed here

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Open access Aug 2026

Methodological insights and clinical outcomes in ALS and FTLD: lessons from the SPIN cohort

Amyotrophic lateral sclerosis (ALS) and frontotemporal lobar degeneration (FTLD) constitute a clinico‐genetic‐neuropathological continuum with marked heterogeneity. Reliable in vivo biomarkers of the disease are lacking. Large, multimodal cohorts are needed to advance biomarker discovery and precision medicine.

Á. Carbayo, J. Turon-Sans, D. Alcolea et al. · Alzheimer's & Dementia · 0 citations

Open access Aug 2026

Pre-dementia clinical trajectories associated with neuronal α-synuclein neuropathologic change: a retrospective cohort study

Heterogeneous pre-dementia trajectories are revealed and support is shown for combining α-synuclein detection with Alzheimer biomarkers, cognitive staging and multidomain clinical measures to improve prognosis and trial design are supported.

I. Illán-Gala, E. Vera, J. Selma-González et al. · Research Square · 0 citations