The aim of the current study was to compare clinical effectiveness and safety profile of Empagliflozin and Dapagliflozin in patients with type 2 diabetes mellitus.This was a prospective comparative study involving a total of n = 120 patients with type 2 diabetes mellitus, who were split into two equal groups; Group A (...
S. S., Maheshwari P, K. K. et al.· World Journal of Current Med...· 0 citations
N-nitrosamine (NA) impurities have emerged as a critical safety concern in pharmaceutical manufacturing since the 2018 discovery of N-nitrosodimethylamine (NDMA) contamination in valsartan, which triggered global recalls and revealed similar issues in metformin, ranitidine, and rifampicin. Classified as Class 1 mutagen...
Sarupruthiya M, Jeevitha D, V. S et al.· International Journal Of Rec...· 0 citations
Alzheimer's disease (AD) is the most common form of senile dementia worldwide and is a progressive and irreversible neurodegenerative disorder, which represents a huge socioeconomic burden on modern healthcare systems. The neuropathology of AD is characterised by a very complex, interconnected cascade of cellular event...
V. S, Sarupruthiya M, Jeevitha D et al.· International Journal Of Rec...· 0 citations
Traditional HPLC method development relies on trial-and-error, one-factor-at-a-time approaches that struggle to capture complex, multivariate interactions among method parameters, often resulting in suboptimal separations and transfer failures. While Design of Experiments and Analytical Quality by Design frameworks add...
M. V, Ramakrishnan M, Gokulamanikandan M et al.· International Journal Of Rec...· 0 citations
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