INTRODUCTION
EF24, a synthetic curcumin derivative, is effective against different forms of cancers but its derivatives are underdeveloped, particularly to improve cytotoxicity and drug-receptor interactions in colorectal cancer.
AREAS COVERED
Nine N-benzoyl EF24 analogs were prepared and identified by Fourier transf...
Fatemeh Khademi Moughari, Ramin Ebrahimi Kiasari, G. Ghavami et al.· Future Medicinal Chemistry· 0 citations
Cutaneous leishmaniasis remains a major unmet medical need due to treatment toxicity, emerging drug resistance, prolonged therapy, and persistent tissue damage.
Lucilia sericata
(Diptera: Calliphoridae) larvae are a promising source of bioactive secretions with antimicrobial and wound-healing properties. Here, we...
Azam Malekian, Naseh Maleki-Ravasan, S. Sardari et al.· Scientific Reports· 0 citations
Findings suggest that Zeaxanthin and β-carotene, identified through a target-based chemoinformatics approach, could be considered as low-toxicity natural compounds with potential for topical or complementary applications in novel antifungal strategies.
Mohadese Panahi Moghadam, S. Sardari, Mohammad Norouzi Nejad et al.· Current Microbiology· 0 citations
Multidrug resistance remains a major obstacle in cancer therapy and is driven by hyperactive efflux transporters and dysregulated signaling pathways. In this study, text mining and network analyses were performed to identify key genes associated with breast cancer drug resistance. Critical regulatory nodes were ide...
Najmeh. Fattahi, C. Eslahchi, F. Ghasemi et al.· npj Systems Biology and Appl...· 0 citations
The main purpose of this paper is to review feature selection methods in QSAR studies, which there are two main categories, supervised and unsupervised.
Fahimeh Motamedi, S. Zareian, S. Sardari et al.· Journal of Nonlinear, Comple...· 0 citations
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