Formulation and Evaluation of a Self-Microemulsifying Drug Delivery System (SMEDDS) of Atazanavir for Enhanced Solubility
The present study was aimed at the formulation and evaluation of a Self-Microemulsifying Drug Delivery System (SMEDDS) of Atazanavir to enhance its solubility and dissolution performance. Atazanavir is a poorly water-soluble antiretroviral drug, and its pH-dependent solubility can limit oral dissolution and absorption....