S. Simjee

Anti-Amnesic and Neuroprotective Potential of a Polyherbal Nutritional Supplement Against Lipopolysaccharide-Induced Neuroinflammation in Rats: Behavioral, Histopathological, and Molecular Insights

Background: The nutritional supplement (NS), composed of Prunus amygdalus, Juglans regia, and Cucumis melo, contains bioactive phytoconstituents such as tocopherol, linoleic acid, and phenolic compounds that contribute to its anti-inflammatory, antioxidant, and neuroprotective potential. The current investigation was c...

Eupatorin interferes with NLRP3 inflammasome activation via modulation of NF-κB signaling pathway in LPS induced macrophages

Serendipitous Discovery of Short Peptides Dimethylammonium Salt Promoting Neural Differentiation

The synthesis and in vitro neuronal growth support activity of a novel series of heptapeptides promote neuronal survival, morphology recovery, increase cell proliferation, and preserve neuronal network integrity under OGD/R and hypoxia/R insult in an in vitro model of ischemic stroke.