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S. Sockanathan

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Open access Sep 2026

Region-dependent regulation of Tau phosphorylation in a mouse model of tauopathy

Hyperphosphorylation of Tau promotes its aggregation and neurofibrillary tangle (NFT) formation, contributing to neuronal dysfunction and neurodegeneration in diseases such as Alzheimer’s Disease (AD) and AD-related dementias (ADRDs). However, the mechanisms underlying dysregulated Tau phosphorylation under pathologica...

Consuelo Jimenez-Ornelas, S. Sockanathan · 0 citations

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