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S. Stavros

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Review Open access Oct 2026

Regulated Cell Death in Reproductive Biology: Mechanisms and Therapeutic Opportunities

Regulated cell death (RCD) has emerged as a fundamental determinant of cellular homeostasis and tissue remodeling, extending far beyond the classical concept of apoptosis. The identification of emerging RCD pathways, including ferroptosis, pyroptosis, necroptosis, cuproptosis, PANoptosis, and autophagy-dependent cell d...

S. Stavros, Efthalia Moustakli, N. Kathopoulis et al. · 0 citations
Review Open access Oct 2026

Exosomes as Molecular Mediators of Reproductive Health: From Infertility to HPV-Related Disease

This review provides a comprehensive overview of the biological roles of exosomes in reproductive physiology, examines their involvement in mechanisms associated with female and male infertility, and discusses their emerging role in human papillomavirus (HPV)-related reproductive disease. Exosomes are small extracellul...

Serafoula-Natalia Siourtou, S. Stavros, M. Daskalaki et al. · 0 citations
Review Open access Sep 2026

Platelet-Rich Plasma in Recurrent Pregnancy Loss: Toward a Precision Medicine Framework for Biologically Guided Patient Selection

Recurrent pregnancy loss (RPL), a multifactorial condition in reproductive medicine, affects approximately 1–3% of couples. Increasing evidence implicates endometrial dysfunction, immune dysregulation, impaired angiogenesis, and oxidative stress (OS) in its pathophysiology, highlighting the need for biologically target...

S. Stavros, A. Potiris, M. Daskalaki et al. · 0 citations
Review Open access Sep 2026

Endocrine and Molecular Mechanisms of Oocyte Aging: From Gonadotropin Signaling to Metabolic and Microenvironmental Dysfunction

Understanding how endocrine dysregulation interacts with metabolic, genomic, and epigenetic alterations and changes in the follicular microenvironment may facilitate the identification of biomarkers and the development of targeted approaches to preserve oocyte quality during reproductive aging.

Maria Fotara, Efthalia Moustakli, M. Daskalaki et al. · 0 citations
Review Open access Aug 2026

Gestational Selenium Exposure and Neonatal Health Outcomes: A Systematic Review of Mortality, Morbidity, and Neurobehavioral Development

Clinical data do not support a widespread protective effect of maternal Se status against adverse neonatal outcomes, and the existing body of evidence is heavily constrained by moderate to very low quality, driven by small sample sizes, insufficient confounding adjustments, and suboptimal exposure assessment timing at...

Nikolina Stachika, E. Tsarna, Eleni Solomou et al. · 0 citations

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