Fueling Early Tumorigenesis: Interplay Between the Exposome, Obesity-Driven Metabolic Dysfunction and Early-Onset Colorectal and Breast Cancer.
Early-onset cancers (EOCs), defined as cancers diagnosed before the age of 50, are increasing globally. This rise cannot be fully explained by improved detection, suggesting the involvement of evolving environmental and lifestyle-related risk factors. In parallel, the global prevalence of obesity has increased substant...