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Review Sep 2026

Fueling Early Tumorigenesis: Interplay Between the Exposome, Obesity-Driven Metabolic Dysfunction and Early-Onset Colorectal and Breast Cancer.

Early-onset cancers (EOCs), defined as cancers diagnosed before the age of 50, are increasing globally. This rise cannot be fully explained by improved detection, suggesting the involvement of evolving environmental and lifestyle-related risk factors. In parallel, the global prevalence of obesity has increased substant...

Mansi Upadhyay, Arianna V. Bastian, T. Cardaci et al. · 0 citations
Open access Jul 2026

Low-fat dietary pattern and dietary advanced glycation end-products intake: a secondary analysis of the Women's Health Initiative randomized trial.

BACKGROUND In the Women's Health Initiative (WHI) Dietary Modification (DM) randomized trial, a low-fat dietary pattern intervention reduced breast cancer mortality (P = 0.02). Higher dietary advanced glycation end-products (dAGE) may be associated with higher breast cancer incidence. In this report, we examined whethe...

M. S. Pichardo, R. Hunt, L. L. Peterson et al. · 0 citations

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