Author

S. Stöcklein

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Open access Oct 2026

Network‐dependent remote effects and local tau burden jointly shape neuronal dysfunction in Alzheimer's disease

Abstract BACKGROUND Tau pathology in Alzheimer's disease (AD) propagates along the brain's connectome, yet the mechanisms by which tau drives neuronal dysfunction remain unclear. We hypothesized that dysfunction primarily emerges in regions close to tau‐harboring epicenters. METHODS One hundred thirty‐one amyloid‐posit...

Lukas Frontzkowski, Sebastian N. Roemer-Cassiano, Johannes S. Gnörich et al. · Alzheimer's & Dementia · 0 citations

Open access Sep 2026

Dynamic [18F]PI-2620 recording facilitates prediction of β-amyloid positivity and simultaneous staging of tau and neurodegeneration

Dynamic [18F]PI-2620 PET imaging facilitates assessment of the β-amyloid status and regional staging of tau and neurodegeneration during a single acquisition, and may reduce radiation exposure, streamline diagnostic workflows, and facilitate personalized disease profiling.

Johannes S. Gnörich, J. Kusche-Palenga, Agnes Kling et al. · Molecular Neurodegeneration · 0 citations

Open access Aug 2026

Investigating changes in the blood-brain barrier in schizophrenia spectrum disorders: design and methodology of a longitudinal dynamic contrast-enhanced MRI study

The IMPACT study aims to elucidate BBB alterations in SSDs and to support stratification approaches in precision psychiatry by providing a longitudinal, BBB-specific neuroimaging framework embedded in a deep phenotyping infrastructure.

A. Wendl, Amelie Zöllinger, Daniel Lukas et al. · European Archives of Psychia... · 0 citations