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Open access Sep 2026

Trends in the incidence of atrial fibrillation and the prescription of oral anticoagulants in adults with chronic obstructive pulmonary disease in UK primary care (2010–2022): a cohort study

Summary Background Understanding the burden of atrial fibrillation (AF) and oral anticoagulant (OAC) use in patients with chronic obstructive pulmonary disease (COPD) is important for stroke prevention in this high-risk population. We assessed trends in AF incidence and OAC initiation among patients with COPD in UK pri...

Brianna Murray, S. Beradid, Pierre Ernst et al. · 0 citations
Open access Sep 2026

Influenza vaccine effectiveness in patients with chronic obstructive pulmonary disease: a cohort study emulating a randomized trial.

OBJECTIVES Many observational studies of influenza vaccine effectiveness have faced issues of residual confounding and immortal time bias. We aimed to assess the effectiveness in people with COPD, using a novel study design to address these methodological challenges. METHODS We conducted a cohort study emulating a ra...

S. Galmiche, S. Dell'Aniello, L. Lévesque et al. · 0 citations
Sep 2026

Effectiveness of GLP-1 receptor agonists to prevent obstructive sleep apnea in patients with type 2 diabetes: active comparator, new user cohort study.

RATIONALE Obstructive sleep apnea (OSA) is highly prevalent in type 2 diabetes (T2D), sharing metabolic risk factors, notably obesity, and increased cardiovascular outcomes. Glucagon-like peptide-1 receptor agonists (GLP-1RAs) have been shown to reduce OSA severity in clinical trials but their role in preventing incide...

Charles Khouri, S. Dell'Aniello, C. Jambon-Barbara et al. · 0 citations
Aug 2026

Effectiveness of beta-blockers in COPD and CVD: Real-world effects on mortality.

BACKGROUND While beta-blockers are effective at reducing mortality in certain cardiovascular diseases (CVD), their effectiveness in patients with chronic obstructive pulmonary disease (COPD) and CVD is uncertain, particularly with the concurrent use of long-acting β2-agonist bronchodilators (LABA). RESEARCH QUESTION...

S. Suissa, S. Dell'Aniello, C. Renoux et al. · 0 citations

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