Author

S. Taherkhani

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Review Open access Sep 2026

Apigenin-Induced Shifts in Microglial and Astrocytic Polarization: A Potential Therapeutic Strategy for Alzheimer’s Disease

Alzheimer’s disease (AD) is a progressive neurodegenerative disorder characterized by amyloid-β accumulation, tau pathology, synaptic failure, neurovascular dysfunction, mitochondrial injury and chronic neuroinflammation. While amyloid and tau remain central pathological features, the inflammatory state of the brain is...

F. Nikbakht, S. Taherkhani, Fatemeh Jamaliaghdam Dozdozan et al. · SVOA Neurology · 0 citations

Review Open access Aug 2026

Investigating the Mechanistic Role of piRNA Dysregulation in Amyloid-beta Toxicity and Tau Pathology in Alzheimer’s Disease Pathophysiology: Implications for Therapeutic Targets

This review synthesizes current knowledge regarding piRNA dysregulation in AD, examining mechanistic links between piRNA loss, transposable element activation, Aβ toxicity, and tau pathology while evaluating therapeutic implications.

S. Taherkhani, Zeynab Sharifiaghdam, Parnian Amani · SVOA Neurology · 0 citations

Review Aug 2026

Neuroinflammatory pathways linking pain and rehabilitation outcomes in schizophrenia: a narrative review.

A narrative review examines clinical, preclinical, and translational studies addressing the role of neuroinflammation in schizophrenia, with a specific focus on microglial and astrocytic activation, cytokine signaling, oxidative stress pathways, and their interactions with central pain processing circuits.

Sanaz Sedghi Esfahani, Elmira Mahdinia, Setareh Dehkhodaei et al. · Pain Management · 0 citations