Open access
Aug 2026
Loss of GdpP function in Staphylococcus aureus confers β-lactam-specific antibiotic tolerance and promotes invasive infection
It is demonstrated that an enhanced level of cyclic-di-AMP (CDA), which results from GdpP loss-of-function mutations, promotes tolerance specifically to the β-lactam class of antibiotics in Staphylococcus aureus.
V.D. Hayatnagarkar, S. Giulieri, Raymond Poon et al.
· bioRxiv · 0 citations