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Author

S. Trouillet-Assant

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Open access Oct 2026

Sustained type I interferon activity and N-antigenemia form a vicious cycle during severe COVID-19.

BACKGROUND Although antigenemia is associated with poor outcomes in respiratory viral infections, the underlying mechanisms driving viral bloodstream dissemination remain not fully understood. Herein, we aimed to characterise SARS-CoV-2 nucleocapsid (N)-antigenemia kinetics in patients with severe COVID-19. We also sou...

W. Mouton, K. Saker, Priscille Franc et al. · 0 citations
Jul 2026

Complement augments antibody neutralization of SARS-CoV-2 variants.

The data show that complement potentiates the ability of antispike antibodies to neutralize immune-evasive SARS-CoV-2 variants and in sera from individuals with severe COVID-19, both complement-mediated neutralization and anti-S2 antibody levels were associated with improved survival.

M. Jungbauer-Groznica, Pierre Rosenbaum, I. Staropoli et al. · 1 citation

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