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S. Velayudhan

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Open access Nov 2026

Integrated transcriptomic and proteomic profiling of RXRA-overexpressing chronic myeloid leukemia cells identifies protein kinase D as a candidate target for imatinib sensitization

Retinoid-X-receptor alpha ( RXRA ) is downregulated in chronic myeloid leukemia (CML). We previously demonstrated that overexpression of RXRA sensitizes CML cells to imatinib, but the mechanisms underlying this effect remain undefined. To characterize the molecular programs associated with RXRA-med...

Rakhi Thalayattu Vidhyadharan, R. Illangeswaran, B. Rajamani et al. · 0 citations

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