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2026

Integrated 3D-QSAR, Molecular Docking, Molecular Dynamics, DFT, In Vitro, and In Vivo Evaluation of Benzylidene-Thiazolidinedione Derivatives as Aldose Reductase Inhibitors

Benzylidene-thiazolidinedione derivatives (SA01-SA12) were designed and synthesized using structure-based 3D-QSAR (R² = 0.819, Q² = 0.537) and pharmacophore modeling techniques to discover potent ALR2 inhibitors. Molecular docking analyses revealed that...

Anita Kumari, S. Verma, Preety Kumari et al. · 0 citations

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