Open access
Sep 2026
Intracellular Ca2+ balances the anti-inflammatory potential of IL-33-activated mast cells (MCs).
IL-33 is an alarmine released upon tissue injury. Mast cells (MCs) highly express the IL-33 receptor T1/ST2 (IL-33R) and are thus highly susceptible to released IL-33. Activation of the IL-33R on MCs induces the MyD88-dependent activation of the TAK1-IKK2-p65/RelA signaling pathway, ERK1/2 and p38 which together mediat...
S. Wagner, Claudia Küchler, K. Hornung et al.
· Cell Calcium · 0 citations