Author

S. Watanuki

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Open access Sep 2026

Genome-Wide Identification and KASP Validation of Two Host Genetic Loci Associated with Bovine Leukemia Virus Proviral Load

The proviral load (PVL) of bovine leukemia virus (BLV) is associated with viral transmission and disease progression to BLV-induced enzootic bovine leukosis and is influenced by genetic polymorphisms of the bovine leukocyte antigen (BoLA)-DRB3 gene. However, its host genetic determinants remain partially defined becaus...

Ying-Bao Ye, S. Watanuki, Fumihiro Nagata et al. · Pathogens · 0 citations

Open access Aug 2026

In vitro antiviral effects of an mTORC1 inhibitor targeting the rapamycin-binding protein complex.

The persistent threat of mutable viral pathogens highlights the need for broad-spectrum antiviral drugs that target stable host factors to provide a high genetic barrier to resistance. The mammalian target of rapamycin complex 1 (mTORC1) serves as a central metabolic bottleneck in cellular metabolism. It is commonly co...

Takafumi Yamada, R. Matsuura, S. Watanuki et al. · Microbial Pathogenesis · 0 citations