Thymic carcinoma (TC) is a rare and aggressive malignancy with limited evidence guiding second-line treatment after prior systemic therapy. We evaluated real-world outcomes of second-line systemic therapy in a multicenter cohort.
Adults with unresectable, recurrent, or metastatic TC who received second-lin...
Fatih Kuş, Fatih Atalah, Gökhan Şahin et al.· BMC Cancer· 0 citations
Background/Objectives: The prognosis of metastatic rectal cancer remains poor, and few reliable prognostic biomarkers are available. DHX9 and CD47 have been implicated in colorectal cancer biology, but their prognostic value in metastatic disease remains unclear. We evaluated the associations of DHX9 and CD47 expressio...
Ş. Yaslıkaya, Ş. A. İpek, T. Toyran et al.· Medical Science· 0 citations
These exploratory findings do not support the clinical use of EZH2 as a biomarker at this stage; prospective, multicenter studies using predefined thresholds and standardized immunohistochemical methods are needed to clarify its potential role as a marker complementary to PD-L1.
E. Asarkaya, Hatice Asoğlu, Abdurrahman Aykut et al.· Journal of Clinical Medicine· 0 citations
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