Sabine Obermüller

Tumor Topography Remodels TME Signalling via Compartment-Specific Host–Microbiome–Tumor Crosstalk in Hepatoblastoma

Simple Summary Tumors develop within a complex microenvironment shaped by signals from cancer cells, host tissues, and the microbiome. We combined bacterial and archaeal profiling with host and tumor (xenograft) transcriptomes in orthotopic versus ectopic hepatoblastoma models to examine how tumor location relates to s...