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Sabrina Gambietz

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Open access Sep 2026

Multivalent Ligand–Protein Interactions in DNA‐Confined Compartments: Role of Geometric Match and Electrostatic Screening

Multivalent interactions are widely used to enhance ligand binding to selected proteins, yet their occurrence in spatially confined nanoscale environments has been poorly investigated. Here, we use programable DNA origami nanocompartments to study multivalent interactions within nanosized volumes. In our system, encaps...

Sabrina Gambietz, Pierre Stegemann, A. Jaekel et al. · 0 citations

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