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Author

Sadek Ahmed

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Open access Sep 2026

Advanced hybrid-stabilized cinacalcet nanocrystals for enhanced oral bioavailability: formulation and integrated in vitro/in vivo evaluations

Introduction Cinacalcet (CINA), a Biopharmaceutics Classification System (BCS) Class IV drug, exhibits limited oral bioavailability due to poor aqueous solubility and low intestinal permeability. We aimed to mechanistically enhance the oral bioavailability of CINA through the development of advanced hybrid-stabilized n...

Rawan Gamal Eldin, Salma M. Mosleh, O. Saher et al. · 2 citations
Review Open access Aug 2026

Neurogenesis and neuroplasticity activities of natural products: therapeutic potential in Alzheimer’s disease

Overall, natural products represent promising candidates for managing neurogenesis and neuroplasticity in AD, although further clinical studies are required to validate their therapeutic efficacy.

A. Shaheen, Mou-Sa A. Mai, Merhan O. Hindam et al. · 2 citations
Open access Jul 2026

Innovative hyaluronic acid-decorated quatsomes for enhanced renal targeting: design, optimization and in-vivo biochemical and nephroprotective assessments

The kidney plays a critical role in metabolite excretion, fluid regulation, and homeostasis, yet remains highly vulnerable to structural and functional disorders. Kidney diseases represent a major global health burden, often progressing to chronic complications due to the limited efficacy and poor selectivity of conven...

Sadek Ahmed, Rana M. ElBishbishy, Mohamed A. Sadek et al. · 4 citations

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