Author

Sadia Alvi

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Open access Aug 2026

Structure-guided allosteric modulation of the delta opioid receptor

Opioid analgesics remain essential for pain management but are associated with significant adverse effects, including respiratory depression, tolerance, and dependence. The δ-opioid receptor (δOR) represents a promising therapeutic target for developing safer opioid analgesics with reduced adverse effects compared to c...

J. Mobbs, M. D. Nguyen, Owindeep Deo et al. · Nature Communications · 0 citations