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Author

Sagar Acharya

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Open access Oct 2026

Comparative hepatoprotective and antifibrotic effects of Amaranthus spinosus (Linn.) leaf, stem, and root extracts in oxidative stress-induced murine liver fibrosis

Liver fibrosis is a progressive pathological disease characterised by excessive deposition of extracellular matrix and damage to hepatocellular architecture. Despite increasing therapeutic requirements, existing antifibrotic therapies are limited. Amaranthus spinosus, an ethnomedicinal plant used by many tribal groups...

Sanchari Bhattacharyya, Anjan Kumar Das, Sagar Acharya · 0 citations
Jul 2026

Methanolic extracts of Amaranthus spinosus (Linn.) mitigate TAA-Induced hepatic fibrosis through modulation of inflammatory cytokines and profibrotic signalling.

The root extract of A. spinosus shows strong therapeutic potential as a multi-target agent capable of disrupting the inflammation-fibrosis axis in chronic liver injury, and is demonstrated to exert potent antifibrotic activity by modulating hepatocyte-driven cytokine networks and suppressing redox-sensitive inflammator...

Sanchari Bhattacharyya, Uma Dutta, Anik Pramanik et al. · 0 citations

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