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Author

Sai S. Koka

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2 papers indexed here

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Open access Sep 2026

Membrane Raft Redox Signaling Mediates Trimethylamine N-Oxide-Induced NLRP3 Inflammasome Activation and Endothelial Dysfunction

Trimethylamine-N-oxide (TMAO), a gut microbiota-derived metabolite, is a known risk factor for cardiovascular disease. We previously showed that TMAO induces NLRP3 inflammasome activation and contributes to endothelial dysfunction. However, the upstream mechanisms linking TMAO to inflammasome activation and barrier inj...

M. Haque, M. A. Rahman, I. S. Sandeep et al. · 0 citations
Open access Aug 2026

A novel redox signalling axis mediates nicotine-induced podocyte injury

It is demonstrated that membrane raft-associated redox signalling serves as a critical upstream mechanism driving nicotine-induced NLRP3 inflammasome activation and podocyte injury.

M. A. Rahman, Rishith Yellu, Varnika Pavirala et al. · 0 citations

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