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Author

Salinee Jantrapirom

2 papers indexed here

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Open access Sep 2026

Pre-symptomatic proteomic and metabolomic profiling identifies compensated ER-redox-metabolic adaptation and early nuclear vulnerability in neuronal ERO1L toxicity

Aging progressively challenges neuronal proteostasis, redox homeostasis, and metabolism, yet the molecular changes that precede functional decline remain poorly understood. Endoplasmic reticulum oxidoreductin 1 (ERO1), a key regulator of oxidative protein folding, links endoplasmic reticulum (ER) proteostasis with cell...

L. Lo Piccolo, Ranchana Yeewa, Puttachat Poound et al. · 0 citations
Open access Jul 2026

Context-dependent YEATS-domain inhibition enhances neuronal resilience and improves ALS phenotypes.

The role of the ENL/AF9 YEATS domain is defined using complementary chemical and genetic perturbations and established ENL/AF9 YEATS-domain inhibition as a context-dependent strategy to enhance neuronal resilience with relevance to ALS and related proteotoxic disorders.

Luca Piccolo, Chansunee Panto, Ranchana Yeewa et al. · 1 citation

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