Abstract B141: Anti-Lymphocyte Antigen 6D (LY6D) monoclonal antibody inhibits pancreatic tumor growth in vivo by downregulating the TGFb-Smad2 signaling
Pancreatic ductal adenocarcinoma (PDAC) is the fourth leading cause of cancer-related deaths in the United States and is associated with dismal prognosis. Recent studies revealed that LY6D expression is elevated in PDAC and correlates with poor patient survival. However, the functional role of LY6D in PDAC progressio...