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Author

Salvador Borrós

2 papers indexed here

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Open access Oct 2026

Computationally Guided Engineering of Short Peptides for Targeted RNA-Loaded pBAE Nanoparticles.

Nanoparticles encapsulating therapeutic RNA have emerged as a transformative strategy in precision medicine, enabling a wide range of applications such as gene therapy for rare diseases, the silencing of toxic gene products, and the mobilization of the immune system to induce specific responses ranging from immune tole...

V. Stamenković, Mislav Brajković, Coral García-Fernández et al. · 0 citations
Open access Aug 2026

Position-specific polymeric-coated oncolytic adenovirus improves anti-tumor efficacy and evades neutralizing antibodies in pancreatic cancer models.

The findings indicate that the proposed formulation PEPB - the oncolytic adenovirus AdNuPARc-E site-specifically shielded with OM-PBAE-CRRR/PEG - offers a promising approach to improve tumor targeting after systemic administration, even in the presence of pre-existing neutralizing antibodies.

Marc Otero-Mateo, Francesc Estrany, Daniel Pembaur et al. · 0 citations

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