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Author

Samantha A. DeSando

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Open access Sep 2026

TDP-43 overexpression induces cellular dysfunction and ALS-associated transcriptional changes

This stable, inducible TDP-43 overexpression model and its associated transcriptomic dataset provide a versatile platform for ALS and other TDP-43 proteinopathy research, enabling the investigation of molecular drivers of TDP-43 dysfunction, the identification of potential disease-relevant pharmacological targets, and...

Samantha A. DeSando, K. Mcclay, Amy N. Banks et al. · 0 citations

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