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Samantha N. Fischer

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Open access Jul 2026

DirectContacts2: a wiring diagram of human physical protein interactions

The authors develop a machine learning classifier through the integration of 25,000 proteomics experiments to construct a wiring diagram of human cells, which enables structural modeling of disease-relevant complexes and establishes a highly accurate protein wiring diagram of the cell.

Erin R. Claussen, Miles D. Woodcock-Girard, Samantha N. Fischer et al. · 0 citations