Microbes and microbial metabolites as immunometabolic drivers of the oral potentially malignant disorder microenvironment
Oral potentially malignant disorders (OPMDs) give rise to most oral squamous cell carcinomas (OSCC). Around 8% transform, but no one can tell which. Dysplasia grade, the instrument in current use, varies between observers and predicts transformation poorly, and the burden falls disproportionately on South and Southeast...