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Author

Sameer N. Goyal

3 papers indexed here

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Review Oct 2026

Microglial GPR56 in synaptic pruning: mechanisms, comparative receptor biology, and context-dependent roles in brain disorders.

Microglia regulate synaptic remodelling, eliminating weakened and dysfunctional synapses to maintain circuit development and homeostasis. Adhesion G protein-coupled receptor G1 (ADGRG1/GPR56) has emerged as a distinctive regulator integrating phosphatidylserine recognition, mechano-transduction, and G-protein signallin...

Akshay K. Chaudhari, Sameer N. Goyal · 0 citations
Review Sep 2026

Integrated cellular and molecular mechanisms of neuropsychiatric dysfunction in polycystic ovary syndrome.

Neuropsychiatric conditions such as depression, anxiety, and stress-related disorders are increasingly associated with Polycystic Ovary Syndrome (PCOS). Evidence suggests that these conditions are not only linked to the metabolic features of PCOS but also share common underlying mechanisms, including hormonal imbalance...

Kamini R. Shirasath, Sanjay N. Awathale, Sameer N. Goyal · 0 citations
Aug 2026

Memantine modulates TRPM3-associated glutamatergic signaling via vGLUT2 in a mouse model of obsessive-compulsive disorder.

Obsessive-compulsive disorder (OCD) is a chronic neuropsychiatric disorder involving neuroinflammation, glutamatergic dysregulation, and altered calcium signaling. Our recent work identified transient receptor potential melastatin 3 (TRPM3) channels as key contributors to OCD pathogenesis via modulation of neuroinflamm...

Prerana V Chaudhari, Sanjay N. Awathale, Sachin R. Ahire et al. · 0 citations

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