Sameer S. Kulkarni

Precision Protein Modification via Ligation and Bioconjugation at Selenocysteine

Selenocysteine (Sec), often referred to as the 21st amino acid, is a rare yet essential amino acid found in a small number of naturally occurring selenoproteins that play critical roles in redox regulation, antioxidant defence, and hormone metabolism. Owing to its distinct chemical properties, namely enhanced nucleop...