Open access
Aug 2026
Endothelial PIEZO1 regulates Weibel-Palade body exocytosis.
It is demonstrated that the opening of a mechanosensitive cation channel PIEZO1 on the EC surface triggers rapid WPB exocytosis and a mechanosensitive molecular pathway coupling inflammation with haemostasis is revealed.
Sammy El-Mansi, M. Al-Saegh, Loïc Rolas et al.
· Blood · 0 citations