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Author

Samseera Ummar

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3 papers indexed here

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Aug 2026

Phosphosite-Centric Association of MBD3 and NuRD Complex Based on Meta-Analysis of Global Human Phosphoproteome.

Methyl-CpG-binding domain protein 3 (MBD3) is a member of the methyl-CpG-binding domain (MBD) family, which functions as a scaffold within the nucleosome remodeling and histone deacetylase complex (NuRD). MBD3 has been studied extensively in pluripotency and gene regulation, particularly through chromatin remodeling. E...

Rachael Dsouza, Vaishnavi Gopalakrishnan, Leona Dcunha et al. · 0 citations
Open access Jan 2026

Illuminating the Co‐Phosphoregulatory Network of the Dark Kinase STK10 by Omics Approaches

Serine/threonine‐protein kinase 10 (STK10), an ERM protein kinase, functions as a membrane–cytoskeleton linker and regulates lymphocyte cortical rigidity, cell shape, adhesion, and migration. Despite its emerging relevance in immune regulation and cancer, the phosphoregulatory mechanisms governing STK10 remain poorly u...

Vaishnavi Gopalakrishnan, Amal Fahma, Althaf Mahin et al. · 0 citations
Open access Aug 2026

Functional phosphoproteomic analysis of SMG1 in nonsense-mediated mRNA decay and DNA damage repair in cancer

Findings identify SMG1 as a central phosphorylation hub integrating nonsense-mediated mRNA decay with genome maintenance pathways and provide the first systematic phosphosite-centric framework for understanding its regulation.

Apoorva Pai, Leona Dcunha, Athira Perunelly Gopalakrishnan et al. · 0 citations

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