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Author

Sandrine Hughes

2 papers indexed here

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Open access Sep 2026

A sensitive Interactome-based approach to characterize drug activity in living human cells.

Abnormal protein-protein interactions (PPIs) involving signaling proteins contribute to numerous human diseases. Targeting such aberrant PPIs with selective inhibitory molecules is a promising therapeutic strategy, yet assessing how many PPIs are affected by a candidate drug, and whether inhibition occurs before or aft...

Cindy Kundlacz, C. Forcet, Nawal Hajj Sleiman et al. · 0 citations
Open access Aug 2026

Transposable elements drive phenotypic variation and shape the response to environmental changes in Drosophila melanogaster

Transposable elements (TEs) are ubiquitous repetitive DNA sequences that can mobilise within genomes and may modulate gene expression in an environment-dependent manner. TEs and the safeguarding epigenetic machinery targeting them, can be tuned by environmental fluctuations to influence gene expression by inducing geno...

A. Larue, Alexander A Mauro, Miriam Merenciano et al. · 0 citations

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