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Sang Hee Park

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Open access Aug 2026

All-trans retinoic acid suppresses CD8+ T-cell terminal exhaustion and potentiates anti-PD-1 therapy in glioblastoma

Findings establish ATRA as a modulator of CD8⁺ T-cell exhaustion through the induction of WNT/β-catenin-dependent TCF-1βBD expression, suggesting that ATRA has therapeutic potential for overcoming resistance to ICB in glioma.

In Kang, Yumin Kim, Byeonguk Kang et al. · 0 citations

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