Jul 2026
Luteolin reverses chemoresistance in colorectal cancer cells via TET1/TDG-dependent epigenetic repression of β-catenin.
It is demonstrated that luteolin reverses chemoresistance by suppressing the TET1/TDG-β-catenin axis through epigenetic regulation and modulation of intracellular redox homeostasis, supporting its potential as an adjuvant for CRC chemotherapy.
K. Kang, Mei-Jing Piao, H. Senavirathna et al.
· Food and Chemical Toxicology · 0 citations