Sangkyu Bahn

Thalamofrontal synaptic weakening underlies short-term memory deficits from adolescent NMDAR hypofunction

Thalamofrontal (TF) dysconnectivity is one of the most consistent circuit-level abnormalities reported in patients with schizophrenia and is linked to deficits in short-term memory (STM). However, the biological mechanisms underlying TF weakening remain unclear. Here, we show that repeated adolescent N-methyl-d-asparta...