Validating the neurobiological model of obsessive-compulsive disorder: a brain entropy study using resting-state fMRI.
BACKGROUND AND HYPOTHESIS Obsessive-compulsive disorder (OCD) has been consistently associated with dysfunction within the cortico-striato-thalamo-cortical (CSTC) circuits. Brain entropy (BEN) is a nonlinear measure of the complexity and irregularity of neural signals, including blood oxygen level-dependent (BOLD) time...