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Author

Sanharib Chamoun

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Open access Sep 2026

Plasma cardiac troponin T as a marker of skeletal muscle involvement in amyotrophic lateral sclerosis

Abstract Plasma cardiac troponin T (cTnT) is widely used as a marker of myocardial injury, yet recent studies suggest elevations in amyotrophic lateral sclerosis (ALS). Whether these elevations reflect disease-associated skeletal muscle remodelling remains unresolved. In this translational study, we analysed longitudin...

L. Öijerstedt, Jia-Ning Lin, Aditya Singh et al. · 0 citations
Open access Jul 2026

Plasma cardiac troponin T complements neurofilament light chain by reflecting disease phase and phenotypic variation in amyotrophic lateral sclerosis

While NfL reflects disease aggressiveness, hs-cTnT aligns with disease phase and clinical phenotype, supporting its use as a complementary biomarker for ALS characterisation and monitoring.

Julia Sellin, Linn Öijerstedt, Janina von der Gablentz et al. · 0 citations

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