Open access
2026
Computational screening of natural product inhibitor stargeting the MDM2-p53 interaction: docking and molecular dynamics insights for retinoblastoma therapy.
Findings support Pentamorphone as a promising candidate capable of disrupting the MDM2-p53 interaction and support its further experimental evaluation as a potential therapeutic lead for retinoblastoma characterized by MDM2-mediated suppression of p53.
Yu-Lei Geng, Xiao-Li Liu, Sanjay Kumar et al.
· American journal of translat... · 0 citations